Samenstelling

Ingrediënten per plantaardige 2 capsules
Lepidium peruvianum G. Chacón de Popovici (Maca) droog extract 300mg, Pinus sylvestris L. (Grove den) droog extract 300mg,  L-tyrosine 250mg, Plantaardige capsule ( Hypromellose) Gelatine, Antiklontermiddelen (Magnesiumsilicaat, Magnesiumstearaat, Siliciumdioxide), Ocimum basilicum L. (Basilicum) droog extract 50 mg, Centella asiatica (L.) Urb. (Gotu kola) droog extract 50mg, Commiphora mukul Engl. droog extract (Guggul) 50 mg, Schisandra chinensis (Turcz.) Baill. (Schisandra) droog extract  50 mg

Referenties

Ranilla LG, Kwon YI, Apostolidis E, Shetty K. Phenolic compounds, antioxidant activity and in vitro inhibitory potential against key enzymes relevant for hyperglycemia and hypertension of commonly used medicinal plants, herbs and spices in Latin America. Bioresource Technology. 2010;101(12):4676–4689.

Lopez-Fando, A., et al. “Lepidium peruvianum Chacon restores homeostasis impaired by restraint stress.” Phytother. Res. 2004; 18(6): 471-4.

Li Q, Kobayashi M, Inagaki H, Hirata Y, Li YJ, Hirata K, Shimizu T, Suzuki H, Katsumata M, Wakayama Y, Kawada T, Ohira T, Matsui N, Kagawa T. A day trip to a forest park increases human natural killer activity and the expression of anti-cancer proteins in male subjects. J Biol Regul Homeost Agents. 2010 Apr-Jun;24(2):157-65

Zhang Y, Yu L, Ao M, Jin W. Effect of ethanol extrait of Lepidium meyenii Walp. on osteoporosis in ovariectomized rat. Journal of Ethnopharmacology. 2006;105(1-2):274–279

Li Q, Kobayashi M, Inagaki H, Hirata Y, Li YJ, Hirata K, Shimizu T, Suzuki H, Katsumata M, Wakayama Y, Kawada T, Ohira T, Matsui N, Kagawa T. Pinus sylvestris increases human natural killer activity and the expression of anti-cancer proteins in male subjects. J Biol Regul Homeost Agents. 2010 Apr-Jun;24(2):157-65

Wurtman RJ, Larin F, Mostafapour S, Fernstrom JD. Brain catechol synthesis: control by brain tyrosine concentration. Science 1974;185:183-184. PMID 4276197.

Banderet LE, Lieberman HR. Treatment with tyrosine, a neurotransmitter precursor, reduces environmental stress in humans. Brain Res Bull 22(4) (1989): 759-62.

Nakashima A, et al: Role of N-terminus of tyrosine hydroxylase in the biosynthesis of catecholamines . J Neural Transm. (2009)

Jodko K, Litwinienko G Oxidative stress in the neurodegenerative diseases--potential antioxidant activity of catecholamines . Postepy Biochem. (2010)

Morris JG, Yu S, Rogers QR. Red hair in black cats is reversed by addition of tyrosine to the diet. J. Nutr [Internet]. 2002 Jun.;132(6 Suppl 2):1646S–8S

Bastian TW, Prohaska JR, Georgieff MK, Anderson GW. Perinatal iron and copper deficiencies alter neonatal rat circulating and brain thyroid hormone concentrations. Endocrinology. 2010 Aug;151(8):4055-65.

Bolk N, Visser TJ, Nijman J, et al. Effects of evening vs morning levothyroxine intake: a randomized double-blind crossover trial. Arch Intern Med. 2010 Dec 13;170(22):1996-2003.

Campbell NR, Hasinoff BB, Stalts H, et al. Ferrous sulfate reduces thyroxine efficacy in patients with hypothyroidism. Ann Intern Med. 1992 Dec 15;117(12):1010-3.

Topall G, Laborit H Brain tyrosine increases after treating with prodrugs: comparison with tyrosine . J Pharm Pharmacol. (1989)

Yeghiayan SK, et al.Tyrosine improves behavioral and neurochemical deficits caused by cold exposure . Physiol Behav. (2001)

 Treatment of attention deficit hyperactivity disorder with monoamine amino acid precursors and organic cation transporter assay interpretation
Neri DF, et al: The effects of tyrosine on cognitive performance during extended wakefulness . Aviat Space Environ Med. (1995)
Banderet, L.E., and H.R.Lieberman 1989 Treatment with tyrosine, a neurotransmitter precursor, reduces environmental stress in humans. Brain Res. Bull. 22:759–762.

Hossein Gholami Tilebeni. "Review to Basil Medicinal Plant". International journal of Agronomy and Plant Production. Vol., 2 (1), 5-9, 2011. Accessed October 17th 2013.

 Juliani, H.R. and J.E. Simon. "Antioxidant Activity of Basil". 2002. p. 575–579. In: J. Janick and A. Whipkey (eds.), Trends in new crops and new uses. Accessed October 17th 2013.

Panossian AG. Adaptogens in mental and behavioral disorders. Psychiatr Clin North Am. 2013 Mar;36(1):49-64.

Panossian A, Wikman G. Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity. Curr Clin Pharmacol. 2009 Sep;4(3):198-219.

Wattanathorn J, Mator L, Muchimapura S, et al. Positive modulation of cognition and mood in the healthy elderly volunteer following the administration of Centella asiatica. J Ethopharmacol 2008;116:325-332

Awad R, Levac D, Cybulska P, et al. Effects of  traditionally used anxiolytic botanicals on enzymes of the gamma-aminobutyric acid (GABA) system. Can J Physiol Pharmacol 2007;85:933

Elias, Jason, and Shelagh Ryan Masline. The A to Z Guide to Healing Herbal Remedies. Lynn Sonberg Book Associates, 1996.

Leong PK, Chen N, Ko KM Mitochondrial decay in ageing: 'Qi-invigorating' schisandrin B as a hormetic agent for mitigating age-related diseases . Clin Exp Pharmacol Physiol. (2012)

Chen Y, et al            An immunostimulatory polysaccharide (SCP-IIa) from the fruit of Schisandra chinensis (Turcz.) Baill . Int J Biol Macromol. (2012)

Chen WW, et al. Pharmacological studies on the anxiolytic effect of standardized Schisandra lignans extrait on restraint-stressed mice . Phytomedicine. (2011)

Aslanyan G, et al. Double-blind, placebo-controlled, randomised study of single dose effects of ADAPT-232 on cognitive functions . Phytomedicine. (2010)

Panossian AG, et al. Effects of heavy physical exercise and adaptogens on nitric oxide content in human saliva . Phytomedicine. (1999)