CURCUMA COMPLEX 500MG [Phyto-Therapy]
CURCUMA COMPLEX 500MG
The dry extract of the Turmeric Root Stick used by Natural Energy comes from the Curcuma Longa species, native to India, and is characterized by a high concentration of active ingredients, namely a ratio of 25: 1 to the fresh plant. Standardized to 95% of Curcuminoids, the three active curcuminoids are present in the rhizome in addition to active essential oils. So 500 mg of turmeric extract (Curcuma longa L.) BCM-95® contains 475 mg Curcuminoids (curcumin, demethoxycurcumin, didemethoxycurcumin) and volatile oils (Tumerone, Atlantone, Zingiberone). The composition of Turmeric extract from Natural Energy has a bioavailability 29 times greater than a standard turmeric extract. Thus higher blood concentrations of the active substances in the body are achieved. Many scientific studies have been carried out with Curcuma longa BCM-95® extract, which proves its safety.
Instructions for use
1 capsule per day.
Do not exceed the recommended daily dose.
Keep out of reach of young children.
Nutritional supplements should not replace a varied and balanced diet and a healthy lifestyle.
Children, pregnant women and women who are breastfeeding, consult your pharmacist before use.
Not to be used during pregnancy or lactation. Consult your doctor or pharmacist with concomitant use of anticoagulants or other medicines. This product is not suitable for people with biliary obstruction. Avoid overdose in case of a stomach ulcer. (Overconsumption can stimulate the stomach lining.) No long-term use without expert advice.
No long-term use without professional advice.
Range of usage
- Natural anti-inflammatory
- Sports performance
- Tendons and joints
CompositionIngredients per capsule
Curcuma longa L. (Turmeric) extract (95% Curcuminoids complex with min.) 500 mg, Gelatine, Filler (Microcrystalline Cellulose), Anti-caking agents (Magnesium stearate, silicon dioxide), Colours (Titanium dioxide, Yellow iron oxide).
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US National Institutes of Health. Trial of Curcumin and Cancer. [Consulté le 29 mars 2011] http://clinicaltrials.gov
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Curcumin as an anti-cancer agent: review of the gap between basic and clinical applications. Bar-Sela G, Epelbaum R, Schaffer M. Curr Med Chem. 2010;17(3):190-7.
Polasa K, Raghuram TC, et al. Effect of turmeric on urinary mutagens in smokers.Mutagenesis 1992 Mar;7(2):107-9.
Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions. Cheng AL, Hsu CH, et al. Anticancer Res. 2001 Jul-Aug;21(4B):2895-900.
Phase II trial of curcumin in patients with advanced pancreatic cancer. Dhillon N, Aggarwal BB, et al. Clin Cancer Res. 2008 Jul 15;14(14):4491-9.
Curcumin and gemcitabine in patients with advanced pancreatic cancer. Epelbaum R, Schaffer M, et al. Nutr Cancer. 2010;62(8):1137-41.
Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer. Sharma RA, McLelland HR, et al. Clin Cancer Res. 2001 Jul;7(7):1894-900.
Perspectives on chemopreventive and therapeutic potential of curcumin analogs in medicinal chemistry. Padhye S, Chavan D, et al. Mini Rev Med Chem. 2010 May;10(5):372-87. Review.
Garcea G, Jones DJ, et al. Detection of curcumin and its metabolites in hepatic tissue and portal blood of patients following oral administration . Br J Cancer. 2004 Mar 8;90(5):1011-5.
New mechanisms and therapeutic potential of curcumin for colorectal cancer. Villegas I, Sánchez-Fidalgo S, et al. Mol Nutr Food Res. 2008 Sep;52(9):1040-61. Review.
Prucksunand C, Indrasukhsri B, et al. Phase II clinical trial on effect of the long turmeric (Curcuma longa Linn) on healing of peptic ulcer.Southeast Asian J Trop Med Public Health 2001 Mar;32(1):208-15
Antioxidant and anti-inflammatory properties of curcumin. Menon VP, Sudheer AR. Adv Exp Med Biol. 2007;595:105-25. Review.
Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research. Jurenka JS. Altern Med Rev. 2009 Jun;14(2):141-53. Review.
Deodhar SD, Sethi R, Srimal RC. Preliminary study on antirheumatic activity of curcumin (diferuloyl methane). Indian J Med Res. 1980 Apr;71:632-4
Thamlikitkul V, Bunyapraphatsara N, et al. Randomized double blind study of Curcuma domestica Val. for dyspepsia.J Med Assoc Thai 1989 Nov;72(11):613-20.
US National Institutes of Health. Curcumin and Alzheimer [Consulté le 29 mars 2011] http://clinicaltrials.gov
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Khajuria A1, Thusu N, Zutshi U. Piperine modulates permeability characteristics of intestine by inducing alterations in membrane dynamics: influence on brush border membrane fluidity, ultrastructure and enzyme kinetics. Phytomedicine. 2002 Apr;9(3):224-31.
Erika Jensen-Jarolim, Leszek Gajdzik, Ines Haberl, Dietrich Kraft, Otto Scheiner, Jürg Graf. Hot Spices Influence Permeability of Human Intestinal Epithelial Monolayers. J. Nutr. 1998 128: 3 577-581.
Christina Schiborr et al., « The oral bioavailability of curcumin from micronized powder and liquid micelles is significantly increased in healthy humans and differs between sexes », Molecular nutrition & food research 58, no 3 (2014): 516–527.
Stephan Dützmann et al., « Intratumoral Concentrations and Effects of Orally Administered Micellar Curcuminoids in Glioblastoma Patients », Nutrition and Cancer 68, no 6 (2016): 943–948.
Ann-Lii Cheng et al., « Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions », Anticancer Res 21, no 4B (2001): 2895–2900.Zhen-Yu He et al., « Upregulation of p53 expression in patients with colorectal cancer by administration of curcumin », Cancer investigation 29, no 3 (2011): 208–213.
Mathilde Bayet-Robert et al., « Phase I dose escalation trial of docetaxel plus curcumin in patients with advanced and metastatic breast cancer », Cancer biology & therapy 9, no 1 (2010): 8–14.
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So Jung Kim et al., « Curcumin stimulates proliferation of embryonic neural progenitor cells and neurogenesis in the adult hippocampus », Journal of Biological Chemistry 283, no 21 (2008): 14497–14505.
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