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MAGNESIUM EXTRA [Minerals]

  • Important for proper functioning of nerves and muscles. 
  • For a healthy psyche.
  • For a normal muscle functioning.
  • For a healthy energy metabolism.
natural energy MAGNESIUM EXTRA
Prijs : € 60 capsules
(CNK: 3070-372)
  at your pharmacist
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MAGNESIUM EXTRA

Magnesium is a very important mineral for the human metabolism. It acts as a cofactor in many energy-producing reactions that take place in the mitochondria, which are the power sources of our body.  Sufficient magnesium levels contribute, therefore, to a normal energy metabolism and, consequently, to a reduction in fatigue and exhaustion.
Sufficient Magnesium is also necessary for the optimal functioning of muscles and nerve cells.

Besides it is also an important resource for the maintenance of bones and teeth.
Also, it contributes to a normal protein synthesis and plays a role in our cell division.
Magnesium also works in our body as a natural tranquilizer, as a kind of anti-stress agent. Magnesium deficiency together with other deficiencies may lead to the development of a number of psychological symptoms such as: nervous exhaustion, irritability, restlessness, lethargy and even depression.
MAGNESIUM EXTRA contains  750mg of Magnesium glycerophosphate per capsule, a natural organic magnesium salt. ‘Magnesium Extra’ has no side effects upon ingestion, unlike the classical, inorganic magnesium salts currently on sale. The traditional inorganic magnesium salts are not natural and, consequently, have side effects, especially in the intestinal area, often involving diarrhoea.

Extra

Instructions for use.
Take 2 capsule per day.

Do not exceed the recommended daily dose.

Keep out of reach of young children.

Nutritional supplements should not replace a varied and balanced diet and a healthy lifestyle.
Children, pregnant women and women who are breastfeeding, consult your pharmacist before use.

Check with simultaneous intake of medicines.

No long-term use without professional advice.

NUT 1429/38

 

Range of usage

•    When feeling tired and lacking energy.
•    To keep the psyche healthy
•    Keeps our muscle function normal.

Composition
Ingredients per 2 vegetable capsules
Vegetable capsule (Hypromellose), Magnesium (Magnesium glycerophosphate) 185.64mg (49.50% RI), Anti-caking agents (Magnesium stearate, Magnesium silicate), Vitamin B6 (Pyridoxine HCL) 4.92mg (351.43% RI)
 
RI: Reference intakes
References
Magnesium for skeletal muscle cramps.
Garrison SR, Allan GM, Sekhon RK, Musini VM, Khan KM.
Cochrane Database Syst Rev. 2012 Sep 12;9:CD009402. doi: 10.1002/14651858.CD009402.pub2. Review.

Nocturnal leg cramps and magnesium.
Allen RE, Kirby KA.
Am Fam Physician. 2012 Aug 15;86(4):350-5. Review.

Update on the relationship between magnesium and exercise.
Nielsen FH, Lukaski HC.
Magnes Res. 2006 Sep;19(3):180-9. Review

Magnesium and muscle performance in older persons: the InCHIANTI study.
Dominguez LJ, Barbagallo M, Lauretani F, Bandinelli S, Bos A, Corsi AM, Simonsick EM, Ferrucci L.
Am J Clin Nutr. 2006 Aug;84(2):419-26

Magnesium and cardiac function.
Konishi M, Tashiro M, Inoue H.
Clin Calcium. 2012 Aug;22(8):1173-9. doi: CliCa120811731179. Review. Japanese.

Oral magnesium supplementation in children with cystic fibrosis improves clinical and functional variables: a double-blind, randomized, placebo-controlled crossover trial.
Gontijo-Amaral C, Guimarães EV, Camargos P.
Am J Clin Nutr. 2012 Jul;96(1):50-6. doi: 10.3945/ajcn.112.034207. Epub 2012 May 30

Magnesium used in bioabsorbable stents controls smooth muscle cell proliferation and stimulates endothelial cells in vitro.
Sternberg K, Gratz M, Koeck K, Mostertz J, Begunk R, Loebler M, Semmling B, Seidlitz A, Hildebrandt P, Homuth G, Grabow N, Tuemmler C, Weitschies W, Schmitz KP, Kroemer HK.
J Biomed Mater Res B Appl Biomater. 2012 Jan;100(1):41-50. doi: 10.1002/jbm.b.31918. Epub 2011 Nov 24.

Effects of Magnesium on muscle performance.
Gulick DT, Agarwal M, Josephs J, Reinmiller A, Zimmerman B.
J Strength Cond Res. 2012 Sep;26(9):2478-83. doi: 10.1519/JSC.0b013e31823f2863.

Prevention of vascular calcification: the role of magnesium.
Cozzolino M.
G Ital Nefrol. 2011 Sep-Oct;28(5):472. Italian. No abstract available.

Magnesium added to bupivacaine prolongs the duration of analgesia after interscalene nerve block.
Lee AR, Yi HW, Chung IS, Ko JS, Ahn HJ, Gwak MS, Choi DH, Choi SJ.
Can J Anaesth. 2012 Jan;59(1):21-7. doi: 10.1007/s12630-011-9604-5. Epub 2011 Oct 20.

Magnesium deficiency up-regulates Myod expression in rat skeletal muscle and C2C12 myogenic cells.
Furutani Y, Funaba M, Matsui T.
Cell Biochem Funct. 2011 Oct;29(7):577-81. doi: 10.1002/cbf.1790. Epub 2011 Aug 19.

Magnesium reduces calcification in bovine vascular smooth muscle cells in a dose-dependent manner.
Kircelli F, Peter ME, Sevinc Ok E, Celenk FG, Yilmaz M, Steppan S, Asci G, Ok E, Passlick-Deetjen J.
Nephrol Dial Transplant. 2012 Feb;27(2):514-21. doi: 10.1093/ndt/gfr321. Epub 2011 Jul 12.

Myocardial extraction of intracellular magnesium and atrial fibrillation after coronary surgery.
Abdel-Massih TE, Sarkis A, Sleilaty G, El Rassi I, Chamandi C, Karam N, Haddad F, Yazigi A, Madi-Jebara S, Yazbeck P, El Asmar B, Ashoush R, Jebara V.
Int J Cardiol. 2012 Oct 4;160(2):114-8. doi: 10.1016/j.ijcard.2011.04.015. Epub 2011 May 7

Chronic magnesium deficiency decreases tolerance to hypoxia/reoxygenation injury in mouse heart.
Watanabe M, Shinohara A, Matsukawa T, Chiba M, Wu J, Iesaki T, Okada T.
Life Sci. 2011 Apr 11;88(15-16):658-63. doi: 10.1016/j.lfs.2011.01.027. Epub 2011 Feb 18.

The relation between blood and tissue magnesium levels and development of atrial fibrillation after coronary artery bypass surgery.
Sahin V, Kaplan M, Bilsel S, Filizcan U, Cetemen S, Bayserke O, Bilgiç Alkaya D, Eren E.
Anadolu Kardiyol Derg. 2010 Oct;10(5):446-51. doi: 10.5152/akd.2010.144.

Effects of sex and short-term magnesium supplementation on stress responses and longissimus muscle quality characteristics of crossbred cattle.
Bass PD, Engle TE, Belk KE, Chapman PL, Archibeque SL, Smith GC, Tatum JD.
J Anim Sci. 2010 Jan;88(1):349-60. doi: 10.2527/jas.2009-2264. Epub 2009 Sep 25.

Arrhythmogenic threshold of the myocardium under conditions of magnesium deficiency.
Spasov AA, Iezhitsa IN, Kharitonova MV, Gurova NA.
Bull Exp Biol Med. 2008 Jul;146(1):63-5.

Preventive role of magnesium on skeletal muscle ischemia-reperfusion injury-an experimental study.
Gormus ZI, Ergene N, Toy H, Baltaci AK, Mogulkoc R.
Biol Trace Elem Res. 2009 Feb;127(2):183-9. doi: 10.1007/s12011-008-8228-2. Epub 2008 Sep 19

Magnesium ion inhibits spontaneous and induced contractions of isolated uterine muscle.
Tica VI, Tica AA, Carlig V, Banica OS.
Gynecol Endocrinol. 2007 Jul;23(7):368-72

Effect of magnesium on reactive oxygen species production in the thigh muscles of broiler chickens.
Liu YX, Guo YM, Wang Z.
Br Poult Sci. 2007 Feb;48(1):84-9

Effect of magnesium sulfate on contractile force and intracellular calcium concentration in pregnant human myometrium.
Fomin VP, Gibbs SG, Vanam R, Morimiya A, Hurd WW.
Am J Obstet Gynecol. 2006 May;194(5):1384-90

Sensitivities of rat primary sensory afferent nerves to magnesium: implications for differential nerve blocks.
Vastani N, Seifert B, Spahn DR, Maurer K.
Eur J Anaesthesiol. 2013 Jan;30(1):21-8. doi: 10.1097/EJA.0b013e32835949ab

Magnesium treatment for neuroprotection in ischemic diseases of the brain.
Westermaier T, Stetter C, Kunze E, Willner N, Raslan F, Vince GH, Ernestus RI.
Exp Transl Stroke Med. 2013 Apr 25;5(1):6. doi: 10.1186/2040-7378-5-6

Magnesium sulphate for women at term for neuroprotection of the fetus.
Nguyen TM, Crowther CA, Wilkinson D, Bain E.
Cochrane Database Syst Rev. 2013 Feb 28;2:CD009395. doi: 10.1002/14651858.CD009395.pub2. Review.

Magnesium in the treatment and prevention of cerebrovascular disease].
Akarachkova ES, Vershinina SV, Kotova OV.
Kardiologiia. 2012;52(9):80-6. Review. Russian

Role of magnesium in nerve tissue.
Torimitsu K, Furukawa Y, Tsukada S.
Clin Calcium. 2012 Aug;22(8):1197-203. doi: CliCa120811971203. Review. Japanese

Magnesium sulfate treatment decreases the initial brain damage alterations produced after perinatal asphyxia in fetal lambs.
Goñi-de-Cerio F, Alvarez A, Lara-Celador I, Alvarez FJ, Alonso-Alconada D, Hilario E.
J Neurosci Res. 2012 Oct;90(10):1932-40. doi: 10.1002/jnr.23091. Epub 2012 Jun 20

Alcohol intoxication may exacerbate the effects of blunt cranial trauma through changes in brain free magnesium levels.
Vink R, Byard RW.
J Forensic Sci. 2012 Jul;57(4):979-82. doi: 10.1111/j.1556-4029.2012.02108.x. Epub 2012 Feb 28

Magnesium for cardiovascular health: time for intervention.
Song Y, Liu S.
Am J Clin Nutr. 2012 Feb;95(2):269-70. doi: 10.3945/ajcn.111.031104. Epub 2012 Jan 4. No abstract available

Magnesium for neuroprotection in birth asphyxia.
Gathwala G, Khera A, Singh J, Balhara B.
J Pediatr Neurosci. 2010 Jul;5(2):102-4. doi: 10.4103/1817-1745.76094

Neuroprotective effect of magnesium sulfate treatment on fetal brain in experimental intrauterine ischemia reperfusion injury.
Solaroglu A, Suat Dede F, Gelisen O, Secilmis O, Dede H.
J Matern Fetal Neonatal Med. 2011 Oct;24(10):1259-61. doi: 10.3109/14767058.2011.572202. Epub 2011 Apr 19

Magnesium ions prevent the development of hyperkinesia evoked by administration of picrotoxin into the rat neostriatum.
Yakimovskii AF, Varshavskaya VM.
Neurosci Behav Physiol. 2007 Oct;37(8):821-6.

Molecular-biological basics of neuroprotection effects of magnesium.
Gromova OA, Torshin IIu, Kalacheva AG, Kuramshina DB.
Zh Nevrol Psikhiatr Im S S Korsakova. 2011;111(12):90-101. Review. Russian. No abstract available

Effect of magnesium sulfate on characteristics of cerebral hemodynamics under conditions of postischemic brain injury].
Ole?nikova ON, Makarova LM, Pogorely? VE.
Eksp Klin Farmakol. 2010 Sep;73(9):17-9. Russia

Neuroprotective effects of magnesium-sulfate on ischemic injury mediated by modulating the release of glutamate and reduced of hyperreperfusion.
Kang SW, Choi SK, Park E, Chae SJ, Choi S, Jin Joo H, Lee GJ, Park HK.
Brain Res. 2011 Jan 31;1371:121-8. doi: 10.1016/j.brainres.2010.11.057. Epub 2010 Nov 25
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